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Three distinct NOS isoforms are expressed in the lung (Van Den Berg et al., 2018)

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The carcinogenic action of UVA which makes up approximately 95% of the terrestrial UV spectrum, is mainly through indirect damage caused by the generation of reactive oxygen species (ROS), while UVB, which makes up less than 5% of the terrestrial spectrum, is a potent mutagen that directly alters nucleotide structure in DNA (1, 2)